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Si la tension artérielle n'est pas suffisamment abaissée avec une dose de 25 mg /jour, un traitement combiné avec un autre médicament antihypertenseur est recommandé.

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And that is the reason that 724 out of 4316 Russian athletes tested were found to be using it in 2015 (before it was prohibited).

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The bias may still be large for small samples ( N less than 10). The RU-486/Cytotec combination causes an abortion 95 percent of the time.